Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD


Skin cancer is the most common type of cancer. It is estimated that about 80% of non-melanoma skin cancers are of the basal cell carcinoma subtype. The FDA has recently approved Novartis Odomzo® (sonidegib) for the treatment of locally advanced basal cell carcinoma for adult patients who are not candidates for surgery or radiation therapy or whose disease has recurred.

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Viruses are small agents that only replicate inside living cells of the organism they infect. Some of them, called oncolytic viruses preferentially infect and kill cancer cells. Their use has been exploited in cancer therapy since early clinical trial studies in the 1940s-50s. However, for several years research in the field was delayed due to the lack of adequate technology. Recent advances in genetic engineering sped up research into the application of viruses for therapeutic uses. Canadian scientists have launched earlier this month the world's first clinical trial that uses a combination of two viruses to attack and kill cancer cells, and at the same time stimulate an anticancer...

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A wealth of studies supports the notions that a high-fat-diet causes obesity and that developing type 2 diabetes is one of the consequences of being overweight. However, an increasing proportion of the population from developing countries seem to be at high risk of becoming obese or diabetic despite eating a normal diet. A new study published last week on Cell Metabolism contributes to the understanding of the role played by evolution in this phenomenon.

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Unlike some other cancer forms death rates from pancreatic cancer have been continuously raising due to a persistent absence of effective treatments beyond surgery. Inability to screen has also significantly limited progress-making for this tumor type. Typically by the time it’s diagnosed, it has already spread. The prestigious scientific journal Nature reported a new molecular study of pancreatic tumors that exploits the use of liquid biopsies to detect proteins from exosomes, tiny vesicles collected from blood samples of pancreatic cancer patients, bringing new hopes for early diagnosis.

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