Blog

Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Cvmd

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October 5, 2018 Artificial Intelligence for Life Science Diagnostics There are multiple forms of artificial intelligence (AI), including deep learning, neural networks, Bayesian networks, and evolutionary algorithms. Here’s how AI approaches are currently being applied across life science and in metabolic disease research. LEARN MORE
September 11, 2018 Using Plasma Ceramides to Predict Coronary Artery Disease Cardiovascular disease (CVD) is the number one cause of death globally, making improved prognostic disease indicators ... LEARN MORE
August 7, 2018 Preclinical Research Models of NAFLD/NASH Most preclinical models of NAFLD/NASH are limited to studying specific aspects of the disease. In this blog post, you ... LEARN MORE
August 2, 2018 Are Noninvasive Tests Enough for NAFLD/NASH Diagnosis? There is significant interest in validating strategies for the noninvasive evaluation of fibrosis in NAFLD/NASH. This ... LEARN MORE
July 31, 2018 From Pathogenesis to Treatment with NAFLD/NASH Non-alcoholic steatohepatitis (NASH) is a hot topic in 2018, with a race to the first approved treatment well under way ... LEARN MORE
July 24, 2018 Improving Cardiac Function with FTY720 – ADA 2018 Our ADA presentations this year included a collaborative poster with Pegasus Bio. The studies used our unique panel of ... LEARN MORE
July 19, 2018 Connecting Inflammation, Diabetes, and Obesity We presented data on our next generation type 2 diabetes (T2D) and obesity rodent models at the ADA Scientific Sessions this year. This included the latest research using the FATZO mouse investigating whether murine models can be used to understand underlying inflammatory mechanisms as they relate to T2D and obesity. LEARN MORE
July 17, 2018 Cardiomyopathy Treatment in Rodent Models – ADA 2018 At ADA 2018, we shared the latest data on our next generation type 2 diabetes (T2D) and obesity rodent models. This ... LEARN MORE
June 19, 2018 DGAT2 Inhibition Doesn’t Affect Plasma Triglycerides, VLDL ApoB In a new study published in Cell Metabolism, McClaren et al utilize a variety of translational models, including both ... LEARN MORE
June 7, 2018 Is an Approved NASH Therapy on the Way? Non-alcoholic steatohepatitis (NASH) is an unmet medical need with no approved therapies and debilitating consequences ... LEARN MORE
March 22, 2018 Are There Are Five Types of Diabetes? New research suggests that there are five types of diabetes, rather than simply Type 1 or Type 2. Understanding diabetes as a group of five distinct diseases could result in improved diagnosis and more effective, personalized treatment. LEARN MORE
March 7, 2018 New Technique Opens Novel Approaches to Insulin Resistance A newly-described technique could open multiple lines of investigation into the pathophysiology and treatment of ... LEARN MORE
October 10, 2017 ADA 2017 Video Poster Review Naturally Diabetic NHP Immune Cell Changes Correspond to Human Type 2 Diabetes While changes in immune cell ... LEARN MORE
September 28, 2017 Impact of Anesthesia During Comprehensive Assessments On Glucose Homeostasis in Diabetic NHPs In the clinic, either an oral glucose (oGTT) or mixed meal (MMTT) tolerance test is used to provide comprehensive ... LEARN MORE
September 14, 2017 First Type 2 Diabetes Publication Comparing Pros and Cons of Two Preclinical Continuous Glucose Monitoring Systems Significant Correlation between Blood Glucose Levels Measured by Glucometer and both the Dexcom G4 Platinum and HD-XG ... LEARN MORE