Blog

Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Cvmd

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December 13, 2018 Obesity, Cancer Development, and Immunotherapy Response How does obesity impact cancer development and immunotherapy response? Find out in our review of cutting-edge combined oncology and metabolic disease studies. LEARN MORE
December 6, 2018 Exercise, Liver Cancer, and NAFLD Mortality Our current understanding of the mechanisms linking obesity and liver cancer is poor. Preclinical research links ... LEARN MORE
November 27, 2018 Advances in Type 1 Diabetes Research and Treatment Review the latest cutting-edge advances in type 1 diabetes including an oral anti-diabetes agent, the artificial ... LEARN MORE
October 5, 2018 Artificial Intelligence for Life Science Diagnostics There are multiple forms of artificial intelligence (AI), including deep learning, neural networks, Bayesian networks, ... LEARN MORE
September 11, 2018 Using Plasma Ceramides to Predict Coronary Artery Disease Cardiovascular disease (CVD) is the number one cause of death globally, making improved prognostic disease indicators ... LEARN MORE
August 7, 2018 Preclinical Research Models of NAFLD/NASH Most preclinical models of NAFLD/NASH are limited to studying specific aspects of the disease. In this blog post, you ... LEARN MORE
August 2, 2018 Are Noninvasive Tests Enough for NAFLD/NASH Diagnosis? There is significant interest in validating strategies for the noninvasive evaluation of fibrosis in NAFLD/NASH. This blog post evaluates the available techniques, including noninvasive echography, and the NHP models available for assessing these new methods. LEARN MORE
July 31, 2018 From Pathogenesis to Treatment with NAFLD/NASH Non-alcoholic steatohepatitis (NASH) is a hot topic in 2018, with a race to the first approved treatment well under way ... LEARN MORE
July 24, 2018 Improving Cardiac Function with FTY720 – ADA 2018 Our ADA presentations this year included a collaborative poster with Pegasus Bio. The studies used our unique panel of ... LEARN MORE
July 19, 2018 Connecting Inflammation, Diabetes, and Obesity We presented data on our next generation type 2 diabetes (T2D) and obesity rodent models at the ADA Scientific Sessions ... LEARN MORE
July 17, 2018 Cardiomyopathy Treatment in Rodent Models – ADA 2018 At ADA 2018, we shared the latest data on our next generation type 2 diabetes (T2D) and obesity rodent models. This included our latest ZDSD rat studies, examining possible therapeutic approaches for cardiomyopathy with the presence of metabolic syndrome. LEARN MORE
June 19, 2018 DGAT2 Inhibition Doesn’t Affect Plasma Triglycerides, VLDL ApoB In a new study published in Cell Metabolism, McClaren et al utilize a variety of translational models, including both ... LEARN MORE
June 7, 2018 Is an Approved NASH Therapy on the Way? Non-alcoholic steatohepatitis (NASH) is an unmet medical need with no approved therapies and debilitating consequences ... LEARN MORE
March 22, 2018 Are There Are Five Types of Diabetes? New research suggests that there are five types of diabetes, rather than simply Type 1 or Type 2. Understanding ... LEARN MORE
March 7, 2018 New Technique Opens Novel Approaches to Insulin Resistance A newly-described technique could open multiple lines of investigation into the pathophysiology and treatment of ... LEARN MORE