April 1, 2020
The Role of Patient-Derived Tumor Organoids in Precision Medicine
Explore how patient-derived tumor organoids are used in the clinic to develop novel precision medicine approaches for guiding and informing treatment options.
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March 16, 2020
Tumor Organoid Q&A: PDXO Models and Immuno-Oncology Applications
Review the key questions and answers on PDX-derived organoids (PDXO) and tumor organoid immuno-oncology applications ...
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March 12, 2020
Top 10 Questions: HUB Organoid Technology and Models
Dr Rajendra Kumari answers the key questions around HUB Organoid technology and tumor organoid models from our recent ...
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March 11, 2020
Top 10 Questions: Liver-Targeted Mitochondrial Uncoupling in NHP Models
Dr. Leigh Goedeke, Postdoctoral Fellow at Yale School of Medicine answers the most popular questions from her recent ...
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March 6, 2020
How to Develop Predictive Cancer Biomarkers
How to develop predictive cancer biomarkers: Explore the different types and classes of cancer biomarker, and the key ...
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March 5, 2020
Comparison Guide: Carbon Tetrachloride Induction and Choline Deficient Diet Models
Compare the key features of popular commercial mouse models for accelerated NAFLD and NASH including fibrosis, such as ...
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February 27, 2020
The Benefits of PDX Models in Head and Neck Cancer Research
Explore why patient-derived xenografts (PDX) are an important model in head and neck cancer research, particularly for studying radiation response and deriving next generation organoids.
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February 25, 2020
Using Organoids to Understand Colorectal Cancer Mechanisms and Development
Learn how healthy tissue and tumor-derived organoids are used to uncover disease mechanisms, here shining a light on ...
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February 20, 2020
Identify Predictive Biomarkers Using Translational Preclinical Models
Explore a variety of methods to identify predictive biomarkers using a range of translational preclinical models ...
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February 18, 2020
Using Liver-Targeted Mitochondrial Uncoupling to Resolve Fatty Liver Disease
Explore how liver-targeted mitochondrial uncoupling is resolving fatty liver disease in preclinical models, with the ...
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February 13, 2020
Targeting KRAS: Finally Drugging the Undruggable?
Targeting KRAS - As promising clinical trial data emerges for KRAS G12C inhibitors, we review the background, recent achievements, and potential future approaches to drugging the once “undruggable” KRAS target.
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February 11, 2020
huPBMC Humanized Mouse Models: De-Risking Graft versus Tumor (GvT) Effects Through a Co-Culture Donor Selection Assay
Explore how to use a donor selection assay to limit the chances of graft vs tumor (GvT) effects when using huPBMC ...
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February 7, 2020
Preclinical Biomarker Discovery: Top 17 Questions
Review key questions on preclinical biomarker discovery from our recent webinar, answered by Mike Batey.
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February 6, 2020
How to Use Mouse Clinical Trials to Reinterpret Clinical Results
Explore how to use mouse clinical trials and analysis by linear mixed models approaches to reinterpret clinical trial ...
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February 4, 2020
How to Quantify Drug Efficacy and Effects in Mouse Clinical Trials
Learn how to correctly quantify drug efficacy and effects in mouse clinical trials using a linear mixed models ...
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