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Blog

Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

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June 20, 2019 Modelling the Full Progression of Type 2 Diabetes | Q&A Learn how we model the full progression of Type 2 diabetes with improved clinical relevance in this Q&A session with Dr. Yixin “Jim” Wang, Senior VP of Cardiovascular and Metabolic Disease Research at CrownBio. LEARN MORE
June 13, 2019 Comparing Traditional Rodent Models for Metabolic Research Explore the main features, advantages, and limitations of common rodent models used in preclinical metabolic disease ... LEARN MORE
June 11, 2019 Orthotopic or Subcutaneous Tumor Homograft Models? When should you use either subcutaneous or orthotopic pancreatic cancer tumor homografts, and where do they best ... LEARN MORE
June 6, 2019 Challenges in Preclinical NASH Modeling Review the current challenges in preclinical NASH drug development in the run-up to International NASH Day. LEARN MORE
June 4, 2019 The Link Between Obesity and Type 2 Diabetes Explore the connections between obesity and type 2 diabetes, and how understanding these links can help improve ... LEARN MORE
May 30, 2019 Key Differences between hPBMC and hCD34 Humanized Mouse Models Learn more about the different human immune cell populations in PBMC and HSC-humanized mouse models, to help select the ... LEARN MORE
May 8, 2019 NASH Induction with CCl4 Learn more about NASH induction through CCl4 administration, and the advantages of inducing NASH in a dysmetabolic background. LEARN MORE
May 7, 2019 Combination Therapies and Tumor Homograft Models Learn more about using tumor homograft models to assess oncology combination regimens, including immunotherapies. LEARN MORE
April 25, 2019 Large-Scale Immunotherapy Screening: How and Why? Learn more about the need for large-scale cancer immunotherapy screens and the different immunocompetent models ... LEARN MORE
April 16, 2019 5 Criteria for Choosing a Contract Research Organization Contract research organizations (CROs) vary in capability, quality, experience, cost, and ease of collaboration. Weigh ... LEARN MORE
April 3, 2019 New Analysis, Model ID, and Modeling Technologies at AACR 2019 In Atlanta this week we’re presenting data on our new analysis platforms and preclinical technologies. This post recaps all the information on new CAR-T cell detection methods, an NGS-based SNP model identification array, data analysis platforms, and improvement on tumor growth mathematical model understanding. LEARN MORE
April 2, 2019 Syngeneic and Tumor Homograft Immuno-Oncology Models at AACR 2019 Recap all our AACR presentations on murine models including bioluminescent orthotopic syngeneic models, syngeneic model ... LEARN MORE
April 1, 2019 Humanized Model Update at AACR 2019 Review all the new data on our humanized target models for human-specific CD40 and combination regimen assessment, and ... LEARN MORE
April 1, 2019 AACR19 Analysis: PDX and PDX-Derived Organoid Models Review all the new data on patient-derived xenograft (PDX) models we’re presenting at AACR 2019 this week, including ... LEARN MORE
March 29, 2019 Tumor Antigen Targets for Personalized Adoptive T Cell Therapies Discover the types of tumor antigens available for T cell therapies, including tumor-specific antigens, ... LEARN MORE