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Blog

Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

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January 31, 2019 How to Test Human-Specific Combination Immunotherapies In Vivo Learn how to evaluate combinations of human-specific checkpoint inhibitors in vivo, with double knock-in humanized drug target mouse models. LEARN MORE
January 29, 2019 Using Syngeneic Tumor Models for POC Studies Syngeneic tumor models are a predictive, high-throughput option for validating novel therapeutic approaches. Here’s how ... LEARN MORE
January 24, 2019 Imaging Orthotopic Disease Explore how preclinical imaging helps visualize disease grown at depth in an in vivo, orthotopic setting. LEARN MORE
January 22, 2019 Tumor Heterogeneity in Preclinical Oncology Models Real tumors are complex and heterogeneous, which has long frustrated efforts to recapitulate the disease in a ... LEARN MORE
January 17, 2019 New Biomarkers to Detect Atrial Fibrillation Review the new data identifying brain natriuretic peptide and FGF-23 as biomarkers for detecting atrial fibrillation in ... LEARN MORE
January 15, 2019 Preclinical Imaging of Non-Solid Tumors Learn how preclinical imaging helps overcome the particular challenges associated with modeling leukemia and other ... LEARN MORE
January 10, 2019 Is Exercise the Key to a Healthy Life? Find out why exercise should be a key part of your healthy lifestyle in 2019. LEARN MORE
January 8, 2019 RAS: Targeting the Impossible Explore the ‘undruggable’ oncology target RAS, inhibitory techniques used on downstream pathways, and the preclinical ... LEARN MORE
January 4, 2019 Selecting Preclinical Models of Diabetes Review the main features you need to consider when selecting preclinical models for type 2 diabetes (T2D) research, ... LEARN MORE
January 2, 2019 Stress Keeping You Up at Night? Blame Your HPA Axis New research into our master “circadian clock” explains why your body responds differently to stress at different times ... LEARN MORE
December 27, 2018 Biomarkers for Dementia and Alzheimer’s Disease Over 47 million people worldwide are living with dementia, the great majority of them due to Alzheimer’s disease (AD). It’s an extremely difficult situation to see someone you love suffering from dementia. LEARN MORE
December 24, 2018 NASH 2018 Review: Improving Awareness and Potential New Therapies A look back at NASH over the course of 2018, with a focus on raising disease awareness and an update on clinical trial ... LEARN MORE
December 20, 2018 Immunotherapy 2018 Review: From the Nobel Prize to Clinical Trial Failures 2018 has been a roller coaster year for immunotherapy, from exciting Nobel Prize news to warning IDO1 clinical trial ... LEARN MORE
December 18, 2018 3 Tips to Navigate a PDX Database Find out how to select the right patient-derived xenograft model database for you, and which features to use for quick ... LEARN MORE
December 13, 2018 Obesity, Cancer Development, and Immunotherapy Response How does obesity impact cancer development and immunotherapy response? Find out in our review of cutting-edge combined ... LEARN MORE