September 22, 2020
T Cell Dysfunction Assays for In Vitro Screening of Immunomodulatory Drug Candidates
Review the latest advances in the recall antigen assay, to provide an optimized system for screening and characterizing immunomodulatory drug candidates, including recapitulating aspects of a suppressed tumor microenvironment (TME).
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September 17, 2020
HUB Technology: The Only Tumor Organoid Platform Available for Oncology Drug Discovery
Explore why adult stem cell (ASC)-derived HUB technology provides the only tumor organoid platform available for ...
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September 15, 2020
Targeting Peroxisome Proliferator-Activated Receptors for NASH Therapy
Review the roles of peroxisome proliferator-activated receptor (PPAR) isotypes in managing hepatic and systemic lipid ...
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September 10, 2020
Genome-Wide RNAseq and Array-Based NanoString Transcriptomic Technologies: Which To Use and When?
Compare the pros and cons of two widely used transcriptomic technologies - genome-wide RNAseq and array-based ...
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September 8, 2020
Targeting the Fibroblast Growth Factor Axis for NASH Therapy
Review the roles of members of the FGF19 subclass of fibroblast growth factor (FGF) hormones in NAFLD and NASH, and the ...
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September 3, 2020
Predicting Clinical Treatment Responses Using HUB Tumor Organoids
Explore the power of HUB tumor organoids in predicting clinical response.
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August 27, 2020
Tumor Organoid Applications in Cancer Research
Explore tumor organoid applications in cancer research including metastasis modeling, drug screening, understanding drug response/resistance and disease mechanisms, based on the unique features of these models.
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August 20, 2020
Why Choose Tumor Organoids vs Other 3D In Vitro Models for Oncology Drug Development
Review the key differences between tumor organoids and other 3D in vitro tumor cell cultures, including spheroids, ...
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August 12, 2020
How to Select the Right In Vivo PDX Using PDX-Derived Organoids (PDXO)
Select the right in vivo PDX: Explore how 3D in vitro tumor organoids are used to guide in vivo PDX model selection.
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July 30, 2020
Obeticholic Acid: Past, Present, and Future?
Review the history of obeticholic acid (OCA) from discovery and proof-of-concept, through clinical trials and approval ...
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July 23, 2020
Digital Pathology
Explore digital pathology, and how it‘s being used for biomarker discovery particularly within immuno-oncology.
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July 16, 2020
Next Generation Sequencing 101
A look at the range of next-generation sequencing technologies available today including whole genome, RNA, and whole ...
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July 10, 2020
Immunogenomics in Oncology Drug Development
Explore the emerging field of immunogenomics and how it’s being used to answer key questions related to immunotherapy ...
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June 11, 2020
DNA Damage Response (DDR)
Explore how various cellular DNA damage response (DDR) and DNA repair pathways are targeted to develop novel anticancer ...
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June 8, 2020
Using Tumor Organoids to Identify Cancer Biomarkers
Review why and how to use 3D in vitro tumor organoids to identify cancer biomarkers.
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