Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

November 20, 2018 Bioelectronic Medicine and Autoimmune Diseases Is bioelectronic medicine the future of treatment for autoimmune diseases like lupus, rheumatoid arthritis, and Crohn’s disease? LEARN MORE
November 15, 2018 Prostate Cancer PDX Models and Oncology Analysis Studies: ENA 2018 This week at ENA 2018, we’re presenting up to date research on our PDX models, including our newly developed prostate ... LEARN MORE
November 15, 2018 Murine Immuno-Oncology Models: ENA 2018 At ENA 2018 we’re presenting new data on our wide range of immuno-oncology (I/O) platforms, with four posters covering ... LEARN MORE
November 14, 2018 Humanized Immuno-Oncology Model Update: ENA 2018 This week, at ENA Dublin 2018, we’re presenting new data from our novel humanized in vivo preclinical platforms. This ... LEARN MORE
October 24, 2018 PDX Study Investigates Cetuximab for Esophageal Cancer Esophageal cancer patients lack targeted agent treatment options, leaving them with a poor prognosis ... LEARN MORE
October 16, 2018 Humanized Mouse Models for Immunotherapy Research Humanized mouse models simulate real patient responses for the evaluation of immunotherapeutic drug candidates. This ... LEARN MORE
October 11, 2018 Tumor Homograft Model Generation: Dissociated Tumor Cells vs Tumor Fragments Novel murine immunocompetent models are needed to overcome issues with commonly used syngeneic tumor models and genetically-engineered animal models. Today we review tumor homograft models and the alternative ways they can be created. LEARN MORE
October 9, 2018 Why PDX Are Needed for Metastatic Breast Cancer Research Metastatic breast cancer is currently incurable, though preclinical research is ongoing. Generating new therapies for ... LEARN MORE
October 5, 2018 Artificial Intelligence for Life Science Diagnostics There are multiple forms of artificial intelligence (AI), including deep learning, neural networks, Bayesian networks, ... LEARN MORE
October 3, 2018 Oncolytic Viruses in Cancer Therapy While viral therapy has existed conceptually for some time, it has only recently gained traction as a promising ... LEARN MORE
September 13, 2018 CAR-T Cell Therapy for Solid Tumors CAR-T cell therapies are currently only approved for blood cancers, but new preclinical research shows promise in using CAR-T cells against solid tumors in gastric cancer. LEARN MORE
September 11, 2018 Using Plasma Ceramides to Predict Coronary Artery Disease Cardiovascular disease (CVD) is the number one cause of death globally, making improved prognostic disease indicators ... LEARN MORE
September 4, 2018 Prostate Cancer Patient-Derived Xenograft (PDX) Models Clinically-relevant prostate cancer patient-derived xenograft (PDX) models are notoriously hard to generate. Here we ... LEARN MORE
August 31, 2018 Why Are Prostate Cancer Preclinical Models Hard to Develop? Prostate cancer is a particularly difficult cancer type to model for preclinical research. Why are prostate cancer ... LEARN MORE
August 17, 2018 Facilitating Drug Discovery with 3D In Vitro Oncology Models Around 95% of new anticancer drugs eventually fail in clinical trials, despite promising results when tested on 2D in ... LEARN MORE