November 20, 2018
Bioelectronic Medicine and Autoimmune Diseases
Is bioelectronic medicine the future of treatment for autoimmune diseases like lupus, rheumatoid arthritis, and Crohn’s disease?
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November 15, 2018
Prostate Cancer PDX Models and Oncology Analysis Studies: ENA 2018
This week at ENA 2018, we’re presenting up to date research on our PDX models, including our newly developed prostate ...
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November 15, 2018
Murine Immuno-Oncology Models: ENA 2018
At ENA 2018 we’re presenting new data on our wide range of immuno-oncology (I/O) platforms, with four posters covering ...
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November 14, 2018
Humanized Immuno-Oncology Model Update: ENA 2018
This week, at ENA Dublin 2018, we’re presenting new data from our novel humanized in vivo preclinical platforms. This ...
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October 24, 2018
PDX Study Investigates Cetuximab for Esophageal Cancer
Esophageal cancer patients lack targeted agent treatment options, leaving them with a poor prognosis ...
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October 16, 2018
Humanized Mouse Models for Immunotherapy Research
Humanized mouse models simulate real patient responses for the evaluation of immunotherapeutic drug candidates. This ...
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October 11, 2018
Tumor Homograft Model Generation: Dissociated Tumor Cells vs Tumor Fragments
Novel murine immunocompetent models are needed to overcome issues with commonly used syngeneic tumor models and genetically-engineered animal models. Today we review tumor homograft models and the alternative ways they can be created.
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October 9, 2018
Why PDX Are Needed for Metastatic Breast Cancer Research
Metastatic breast cancer is currently incurable, though preclinical research is ongoing. Generating new therapies for ...
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October 5, 2018
Artificial Intelligence for Life Science Diagnostics
There are multiple forms of artificial intelligence (AI), including deep learning, neural networks, Bayesian networks, ...
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October 3, 2018
Oncolytic Viruses in Cancer Therapy
While viral therapy has existed conceptually for some time, it has only recently gained traction as a promising ...
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September 13, 2018
CAR-T Cell Therapy for Solid Tumors
CAR-T cell therapies are currently only approved for blood cancers, but new preclinical research shows promise in using CAR-T cells against solid tumors in gastric cancer.
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September 11, 2018
Using Plasma Ceramides to Predict Coronary Artery Disease
Cardiovascular disease (CVD) is the number one cause of death globally, making improved prognostic disease indicators ...
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September 4, 2018
Prostate Cancer Patient-Derived Xenograft (PDX) Models
Clinically-relevant prostate cancer patient-derived xenograft (PDX) models are notoriously hard to generate. Here we ...
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August 31, 2018
Why Are Prostate Cancer Preclinical Models Hard to Develop?
Prostate cancer is a particularly difficult cancer type to model for preclinical research. Why are prostate cancer ...
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August 17, 2018
Facilitating Drug Discovery with 3D In Vitro Oncology Models
Around 95% of new anticancer drugs eventually fail in clinical trials, despite promising results when tested on 2D in ...
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