March 7, 2019
Genetic Abnormality Spectrum in Hematologic Cancers
What have we learned about the genetics of hematological cancers, and how can that be modelled for research and drug discovery?
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March 6, 2019
Using Genetic Features to ID and QC Murine Tumor Models
Learn how unique genetic events can be used to generate a “genetic fingerprint” to ID and QC murine tumor models.
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March 5, 2019
Recognizing and Profiling T Cell Receptors
Learn more about T cell receptors in personalized T cell therapy, including TCR diversity, repertoire, and how TCR are ...
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March 1, 2019
Novel Uses for PDX Models in Preclinical Drug Development
Learn how unique PDX models are used to support clinical drug development, discover predictive gene signatures, and for ...
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February 28, 2019
Challenges and Opportunities in Pancreatic Cancer Research
Learn more about pancreatic cancer -- its associated risk factors, diagnosis, treatment and outcomes -- and current ...
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February 14, 2019
Designing HSC Humanized Model Efficacy Studies
Review some key considerations in humanized model study design for successful preclinical oncology research.
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February 13, 2019
Safety and Efficacy Testing of Anti-Obesity Drugs with NHPs
Learn how NHP models provide a more human disease-relevant platform for enhanced preclinical safety and efficacy evaluation of anti-obesity agents.
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February 12, 2019
Targeting the FGF/FGFR Signaling Axis with PDX Models
Discover the complex range of FGFR family aberrations in cancer and how PDX models are a powerful tool for assessing ...
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February 7, 2019
CD40: Targeting Co-Stimulatory Pathways for Cancer Immunotherapy
Explore the role of CD40 in cancer immunotherapy, including its background, functions, and why combination regimens may ...
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February 6, 2019
Target Engagement Studies with Syngeneic Tumor Models
Syngeneic tumor models are a rapid and high-throughput option for novel drug discovery. Here’s how to use them for ...
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February 5, 2019
Beginners Guide to PBMC Humanized Tumor Models
Discover PBMC-humanized tumor models for short-term immunotherapy assessment studies.
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January 31, 2019
How to Test Human-Specific Combination Immunotherapies In Vivo
Learn how to evaluate combinations of human-specific checkpoint inhibitors in vivo, with double knock-in humanized drug ...
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January 29, 2019
Using Syngeneic Tumor Models for POC Studies
Syngeneic tumor models are a predictive, high-throughput option for validating novel therapeutic approaches. Here’s how ...
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January 24, 2019
Imaging Orthotopic Disease
Explore how preclinical imaging helps visualize disease grown at depth in an in vivo, orthotopic setting.
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January 22, 2019
Tumor Heterogeneity in Preclinical Oncology Models
Real tumors are complex and heterogeneous, which has long frustrated efforts to recapitulate the disease in a ...
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