June 20, 2019
Modelling the Full Progression of Type 2 Diabetes | Q&A
Learn how we model the full progression of Type 2 diabetes with improved clinical relevance in this Q&A session with Dr. Yixin “Jim” Wang, Senior VP of Cardiovascular and Metabolic Disease Research at CrownBio.
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June 13, 2019
Comparing Traditional Rodent Models for Metabolic Research
Explore the main features, advantages, and limitations of common rodent models used in preclinical metabolic disease ...
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June 11, 2019
Orthotopic or Subcutaneous Tumor Homograft Models?
When should you use either subcutaneous or orthotopic pancreatic cancer tumor homografts, and where do they best ...
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June 6, 2019
Challenges in Preclinical NASH Modeling
Review the current challenges in preclinical NASH drug development in the run-up to International NASH Day.
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June 4, 2019
The Link Between Obesity and Type 2 Diabetes
Explore the connections between obesity and type 2 diabetes, and how understanding these links can help improve ...
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May 30, 2019
Key Differences between hPBMC and hCD34 Humanized Mouse Models
Learn more about the different human immune cell populations in PBMC and HSC-humanized mouse models, to help select the ...
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May 8, 2019
NASH Induction with CCl4
Learn more about NASH induction through CCl4 administration, and the advantages of inducing NASH in a dysmetabolic background.
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May 7, 2019
Combination Therapies and Tumor Homograft Models
Learn more about using tumor homograft models to assess oncology combination regimens, including immunotherapies.
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April 25, 2019
Large-Scale Immunotherapy Screening: How and Why?
Learn more about the need for large-scale cancer immunotherapy screens and the different immunocompetent models ...
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April 16, 2019
5 Criteria for Choosing a Contract Research Organization
Contract research organizations (CROs) vary in capability, quality, experience, cost, and ease of collaboration. Weigh ...
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April 3, 2019
New Analysis, Model ID, and Modeling Technologies at AACR 2019
In Atlanta this week we’re presenting data on our new analysis platforms and preclinical technologies. This post recaps all the information on new CAR-T cell detection methods, an NGS-based SNP model identification array, data analysis platforms, and improvement on tumor growth mathematical model understanding.
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April 2, 2019
Syngeneic and Tumor Homograft Immuno-Oncology Models at AACR 2019
Recap all our AACR presentations on murine models including bioluminescent orthotopic syngeneic models, syngeneic model ...
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April 1, 2019
Humanized Model Update at AACR 2019
Review all the new data on our humanized target models for human-specific CD40 and combination regimen assessment, and ...
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April 1, 2019
AACR19 Analysis: PDX and PDX-Derived Organoid Models
Review all the new data on patient-derived xenograft (PDX) models we’re presenting at AACR 2019 this week, including ...
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March 29, 2019
Tumor Antigen Targets for Personalized Adoptive T Cell Therapies
Discover the types of tumor antigens available for T cell therapies, including tumor-specific antigens, ...
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