November 26, 2019
Ask the Expert: Successfully Developing PDX-Derived Organoid (PDXO) Models
Review the key questions on the development of PDX-derived organoids (PDXO) from our recent webinar, answered by Dr. Rajendra Kumari, Global Head of Scientific Communication.
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November 22, 2019
The Importance of Companion Diagnostics
Explore the importance of companion diagnostics (CDx) and the benefits of their early adoption and drug codevelopment.
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November 5, 2019
Cancer Biomarkers: Improving Detection and Treatment
Explore the three main types of cancer biomarkers and their main uses in cancer diagnosis, informing prognosis, and ...
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October 30, 2019
The Biological Equivalence of PDXs and PDXOs
Learn about patient-derived xenograft (PDX) and PDX-derived organoid (PDXO) biological equivalence, based on shared ...
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October 29, 2019
Advances in In Vivo Oncology Models at AACR-NCI-EORTC 2019
In Boston this week we’re presenting all the latest updates across our panels of in vivo oncology models. Catch up with ...
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October 28, 2019
New Organoid Platforms for Oncology and I/O Drug Discovery at AACR-NCI-EORTC 2019
2019 has been an exciting year at CrownBio with the addition of organoid platforms to our portfolio of models and ...
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October 28, 2019
Biomarker Discovery and MOA Evaluation through Genomic and Proteomic Profiling at AACR-NCI-EORTC 2019
This week in Boston we’re presenting data on our new analysis platform and preclinical technologies. This post recaps all the new information on genomic and proteomic profiling of PDX models, our automated biomarker discovery platform, and deep proteomics in syngeneic models to uncover anti-PD-1 mechanism of action.
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October 25, 2019
How to Detect, Characterize, and Evaluate CAR-Ts: Top 13 Questions
Review key questions on preclinical models and rare cell analysis technology for assessing CAR-T cell therapies from ...
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October 24, 2019
Graft-versus-Host Disease: Types and How to Model Them
Review the different types of graft-versus-host disease (GvHD) and the preclinical models (including humanized mice) ...
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October 22, 2019
Dietary Mouse Models of NASH: Comparing the AMLN Diets and the MS-NASH Mouse
Compare the key features of commercial dietary mouse models of NASH, including disease induction by the AMLN and GAN ...
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October 4, 2019
What are PDX-Derived Organoids (PDXOs)?
Learn about PDX-derived organoids, including PDXO establishment and utility in a pioneering drug discovery platform combining the benefits of in vitro PDXO and highly predictive in vivo PDX models.
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September 27, 2019
Preclinical Obesity Study Design: Top 10 Questions
Review the top 10 questions on optimizing preclinical obesity studies and model selection from our recent webinar, ...
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September 19, 2019
Key Discoveries in the Development of Modern HUB Organoids
Learn about the key research discoveries leading to the development of modern HUB Organoids.
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September 17, 2019
Targeting Tumor-Associated Antigens and Tumor-Specific Antigens
Learn more about targeting human tumor-associated antigens (TAAs) or tumor-specific antigens (TSAs) in immunotherapy ...
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September 13, 2019
HUB Tumor Organoids: Top 15 Questions
Review the key questions on HUB tumor organoids from our recent webinar, answered by Dr Sylvia Boj, Hubrecht Organoid ...
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