September 8, 2020
Targeting the Fibroblast Growth Factor Axis for NASH Therapy
Review the roles of members of the FGF19 subclass of fibroblast growth factor (FGF) hormones in NAFLD and NASH, and the emerging NAFLD/NASH therapies targeting this endocrine axis.
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September 3, 2020
Predicting Clinical Treatment Responses Using HUB Tumor Organoids
Explore the power of HUB tumor organoids in predicting clinical response.
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August 27, 2020
Tumor Organoid Applications in Cancer Research
Explore tumor organoid applications in cancer research including metastasis modeling, drug screening, understanding ...
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August 20, 2020
Why Choose Tumor Organoids vs Other 3D In Vitro Models for Oncology Drug Development
Review the key differences between tumor organoids and other 3D in vitro tumor cell cultures, including spheroids, ...
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August 12, 2020
How to Select the Right In Vivo PDX Using PDX-Derived Organoids (PDXO)
Select the right in vivo PDX: Explore how 3D in vitro tumor organoids are used to guide in vivo PDX model selection.
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July 30, 2020
Obeticholic Acid: Past, Present, and Future?
Review the history of obeticholic acid (OCA) from discovery and proof-of-concept, through clinical trials and approval ...
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July 23, 2020
Digital Pathology
Explore digital pathology, and how it‘s being used for biomarker discovery particularly within immuno-oncology.
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July 16, 2020
Next Generation Sequencing 101
A look at the range of next-generation sequencing technologies available today including whole genome, RNA, and whole ...
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July 10, 2020
Immunogenomics in Oncology Drug Development
Explore the emerging field of immunogenomics and how it’s being used to answer key questions related to immunotherapy ...
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June 11, 2020
DNA Damage Response (DDR)
Explore how various cellular DNA damage response (DDR) and DNA repair pathways are targeted to develop novel anticancer ...
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June 8, 2020
Using Tumor Organoids to Identify Cancer Biomarkers
Review why and how to use 3D in vitro tumor organoids to identify cancer biomarkers.
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May 15, 2020
Top 3 Ways to Use Tumor Organoids for Drug Screening
Explore the top 3 ways to use tumor organoids for drug screening: library screening, efficacy quantification screening, ...
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May 7, 2020
Top 4 Applications for Tumor Organoids in Oncology Drug Development
Explore the main applications for tumor organoids in preclinical cancer drug development, driven by the unique features ...
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May 5, 2020
HUB Organoids as Human Cancer Models
Explore the phenotypic and genetic concordance between HUB patient-derived tumor organoids and the primary human ...
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April 30, 2020
How to Use Tumor Organoids for Immuno-Oncology Applications
Explore how to use tumor organoids for immuno-oncology applications, including immunotherapy assessment through ...
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