November 6, 2020
In Vivo Imaging of Syngeneic Models for Immuno-Oncology Studies
Explore how different imaging modalities are used to monitor in vivo immuno-oncology (I/O) studies in syngeneic tumor models.
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October 26, 2020
Applications and Benefits of Engineered Syngeneic Cell Lines
Explore the use and main benefits of engineered syngeneic cell lines for investigating drug targets and biological ...
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October 21, 2020
Meet the CrownBio Team: Dr Marrit Putker, Organoid Research Scientist
Meet the newest member of CrownBio’s organoid team, Marrit Putker, heading up research at our new Utrecht site.
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October 14, 2020
Evaluating Immunotherapy Mechanism of Action with Immune Cell Lineage-Specific DTR Models
Explore how transgenic diphtheria toxin receptor (DTR) preclinical models are used to better understand immunotherapy ...
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October 2, 2020
Next Generation Syngeneic Models: Top 14 Questions
Dr Davy Ouyang, CrownBio Vice President of Scientific Research & Innovation answers the most popular questions from ...
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September 22, 2020
T Cell Dysfunction Assays for In Vitro Screening of Immunomodulatory Drug Candidates
Review the latest advances in the recall antigen assay, to provide an optimized system for screening and characterizing ...
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September 17, 2020
HUB Technology: The Only Tumor Organoid Platform Available for Oncology Drug Discovery
Explore why adult stem cell (ASC)-derived HUB technology provides the only tumor organoid platform available for oncology drug discovery.
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September 10, 2020
Genome-Wide RNAseq and Array-Based NanoString Transcriptomic Technologies: Which To Use and When?
Compare the pros and cons of two widely used transcriptomic technologies - genome-wide RNAseq and array-based ...
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September 3, 2020
Predicting Clinical Treatment Responses Using HUB Tumor Organoids
Explore the power of HUB tumor organoids in predicting clinical response.
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August 27, 2020
Tumor Organoid Applications in Cancer Research
Explore tumor organoid applications in cancer research including metastasis modeling, drug screening, understanding ...
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August 20, 2020
Why Choose Tumor Organoids vs Other 3D In Vitro Models for Oncology Drug Development
Review the key differences between tumor organoids and other 3D in vitro tumor cell cultures, including spheroids, which influences model choice for oncology drug development use.
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August 12, 2020
How to Select the Right In Vivo PDX Using PDX-Derived Organoids (PDXO)
Select the right in vivo PDX: Explore how 3D in vitro tumor organoids are used to guide in vivo PDX model selection.
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July 23, 2020
Digital Pathology
Explore digital pathology, and how it‘s being used for biomarker discovery particularly within immuno-oncology.
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July 16, 2020
Next Generation Sequencing 101
A look at the range of next-generation sequencing technologies available today including whole genome, RNA, and whole ...
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July 10, 2020
Immunogenomics in Oncology Drug Development
Explore the emerging field of immunogenomics and how it’s being used to answer key questions related to immunotherapy ...
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