February 12, 2019
Targeting the FGF/FGFR Signaling Axis with PDX Models
Discover the complex range of FGFR family aberrations in cancer and how PDX models are a powerful tool for assessing new FGFR-targeted therapeutic options.
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February 7, 2019
CD40: Targeting Co-Stimulatory Pathways for Cancer Immunotherapy
Explore the role of CD40 in cancer immunotherapy, including its background, functions, and why combination regimens may ...
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February 6, 2019
Target Engagement Studies with Syngeneic Tumor Models
Syngeneic tumor models are a rapid and high-throughput option for novel drug discovery. Here’s how to use them for ...
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February 5, 2019
Beginners Guide to PBMC Humanized Tumor Models
Discover PBMC-humanized tumor models for short-term immunotherapy assessment studies.
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January 31, 2019
How to Test Human-Specific Combination Immunotherapies In Vivo
Learn how to evaluate combinations of human-specific checkpoint inhibitors in vivo, with double knock-in humanized drug ...
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January 29, 2019
Using Syngeneic Tumor Models for POC Studies
Syngeneic tumor models are a predictive, high-throughput option for validating novel therapeutic approaches. Here’s how ...
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January 24, 2019
Imaging Orthotopic Disease
Explore how preclinical imaging helps visualize disease grown at depth in an in vivo, orthotopic setting.
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January 22, 2019
Tumor Heterogeneity in Preclinical Oncology Models
Real tumors are complex and heterogeneous, which has long frustrated efforts to recapitulate the disease in a ...
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January 17, 2019
New Biomarkers to Detect Atrial Fibrillation
Review the new data identifying brain natriuretic peptide and FGF-23 as biomarkers for detecting atrial fibrillation in ...
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January 15, 2019
Preclinical Imaging of Non-Solid Tumors
Learn how preclinical imaging helps overcome the particular challenges associated with modeling leukemia and other ...
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January 10, 2019
Is Exercise the Key to a Healthy Life?
Find out why exercise should be a key part of your healthy lifestyle in 2019.
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January 8, 2019
RAS: Targeting the Impossible
Explore the ‘undruggable’ oncology target RAS, inhibitory techniques used on downstream pathways, and the preclinical ...
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January 4, 2019
Selecting Preclinical Models of Diabetes
Review the main features you need to consider when selecting preclinical models for type 2 diabetes (T2D) research, ...
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January 2, 2019
Stress Keeping You Up at Night? Blame Your HPA Axis
New research into our master “circadian clock” explains why your body responds differently to stress at different times ...
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December 27, 2018
Biomarkers for Dementia and Alzheimer’s Disease
Over 47 million people worldwide are living with dementia, the great majority of them due to Alzheimer’s disease (AD). ...
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