March 26, 2019
Patient-Derived Organoids (PDOs) for Personalized Cancer Research
Learn more about patient-derived organoids, a unique ex vivo tool enabling personalized cancer research for improved treatment of metastatic disease.
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March 14, 2019
LAG3: A Promising New Cancer Immunotherapy Target
As we continue our discussion of the immune revolution in cancer therapy, we look at the benefits of targeting LAG3, an ...
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March 7, 2019
Genetic Abnormality Spectrum in Hematologic Cancers
What have we learned about the genetics of hematological cancers, and how can that be modelled for research and drug ...
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March 6, 2019
Using Genetic Features to ID and QC Murine Tumor Models
Learn how unique genetic events can be used to generate a “genetic fingerprint” to ID and QC murine tumor models.
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March 5, 2019
Recognizing and Profiling T Cell Receptors
Learn more about T cell receptors in personalized T cell therapy, including TCR diversity, repertoire, and how TCR are ...
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March 1, 2019
Novel Uses for PDX Models in Preclinical Drug Development
Learn how unique PDX models are used to support clinical drug development, discover predictive gene signatures, and for ...
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February 28, 2019
Challenges and Opportunities in Pancreatic Cancer Research
Learn more about pancreatic cancer -- its associated risk factors, diagnosis, treatment and outcomes -- and current research into this understudied disease.
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February 14, 2019
Designing HSC Humanized Model Efficacy Studies
Review some key considerations in humanized model study design for successful preclinical oncology research.
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February 13, 2019
Safety and Efficacy Testing of Anti-Obesity Drugs with NHPs
Learn how NHP models provide a more human disease-relevant platform for enhanced preclinical safety and efficacy ...
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February 12, 2019
Targeting the FGF/FGFR Signaling Axis with PDX Models
Discover the complex range of FGFR family aberrations in cancer and how PDX models are a powerful tool for assessing ...
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February 7, 2019
CD40: Targeting Co-Stimulatory Pathways for Cancer Immunotherapy
Explore the role of CD40 in cancer immunotherapy, including its background, functions, and why combination regimens may be key to targeting this checkpoint.
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February 6, 2019
Target Engagement Studies with Syngeneic Tumor Models
Syngeneic tumor models are a rapid and high-throughput option for novel drug discovery. Here’s how to use them for ...
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February 5, 2019
Beginners Guide to PBMC Humanized Tumor Models
Discover PBMC-humanized tumor models for short-term immunotherapy assessment studies.
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January 31, 2019
How to Test Human-Specific Combination Immunotherapies In Vivo
Learn how to evaluate combinations of human-specific checkpoint inhibitors in vivo, with double knock-in humanized drug ...
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January 29, 2019
Using Syngeneic Tumor Models for POC Studies
Syngeneic tumor models are a predictive, high-throughput option for validating novel therapeutic approaches. Here’s how ...
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