October 5, 2018
Artificial Intelligence for Life Science Diagnostics
There are multiple forms of artificial intelligence (AI), including deep learning, neural networks, Bayesian networks, and evolutionary algorithms. Here’s how AI approaches are currently being applied across life science and in metabolic disease research.
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October 3, 2018
Oncolytic Viruses in Cancer Therapy
While viral therapy has existed conceptually for some time, it has only recently gained traction as a promising ...
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September 13, 2018
CAR-T Cell Therapy for Solid Tumors
CAR-T cell therapies are currently only approved for blood cancers, but new preclinical research shows promise in using ...
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September 11, 2018
Using Plasma Ceramides to Predict Coronary Artery Disease
Cardiovascular disease (CVD) is the number one cause of death globally, making improved prognostic disease indicators ...
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September 4, 2018
Prostate Cancer Patient-Derived Xenograft (PDX) Models
Clinically-relevant prostate cancer patient-derived xenograft (PDX) models are notoriously hard to generate. Here we ...
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August 31, 2018
Why Are Prostate Cancer Preclinical Models Hard to Develop?
Prostate cancer is a particularly difficult cancer type to model for preclinical research. Why are prostate cancer ...
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August 17, 2018
Facilitating Drug Discovery with 3D In Vitro Oncology Models
Around 95% of new anticancer drugs eventually fail in clinical trials, despite promising results when tested on 2D in vitro preclinical models. New models that better mimic tumor biology in vivo can facilitate more efficient and translatable drug discovery research.
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August 7, 2018
Preclinical Research Models of NAFLD/NASH
Most preclinical models of NAFLD/NASH are limited to studying specific aspects of the disease. In this blog post, you ...
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August 2, 2018
Are Noninvasive Tests Enough for NAFLD/NASH Diagnosis?
There is significant interest in validating strategies for the noninvasive evaluation of fibrosis in NAFLD/NASH. This ...
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July 31, 2018
From Pathogenesis to Treatment with NAFLD/NASH
Non-alcoholic steatohepatitis (NASH) is a hot topic in 2018, with a race to the first approved treatment well under way ...
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July 26, 2018
IDO to I DON’T – IDO1 Inhibitor Development News
As targeted immuno-oncology agents make impressive strides in cancer treatment, researchers are looking for agents that can augment response or overcome patient resistance. While small molecule IDO1 (indoleamine 2,3-dioxygenase-1) inhibitors were an early favorite among commercial drug discovery programs, disappointing Phase 3 clinical trials drove a rapid ...
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July 24, 2018
Improving Cardiac Function with FTY720 – ADA 2018
Our ADA presentations this year included a collaborative poster with Pegasus Bio. The studies used our unique panel of ...
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July 19, 2018
Connecting Inflammation, Diabetes, and Obesity
We presented data on our next generation type 2 diabetes (T2D) and obesity rodent models at the ADA Scientific Sessions ...
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July 17, 2018
Cardiomyopathy Treatment in Rodent Models – ADA 2018
At ADA 2018, we shared the latest data on our next generation type 2 diabetes (T2D) and obesity rodent models. This ...
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July 5, 2018
Personalized Cancer Immunotherapy
Precision medicine and immunotherapy are currently two of the hottest areas of cancer research. How can immuno-oncology ...
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