Blog

Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

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September 13, 2016 Obesity Linked To Self-Eating Beige Fat Humans, like all mammals, have two types of fat with completely opposite functions: white, which stores energy and when present in excess is linked with diabetes and obesity; and brown, which produces heat by burning energy and is associated with leanness. Recently, a third type of fat was discovered within white fat, called beige fat. Beige fat cells can ... LEARN MORE
September 6, 2016 All About Leukemia for Childhood Cancer Month September is Childhood Cancer Awareness Month, raising awareness and providing time for discussion on this deadly group ... LEARN MORE
August 23, 2016 Put Your Glasses On, Tumor Pharmacology Goes 3D Attrition rates in oncology drug development are higher than in other disease areas, with almost 95% of compounds ... LEARN MORE
August 2, 2016 Study Finds Perfect Therapeutic Match To Fight a Common Form of Leukemia Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer, characterized by an excessive ... LEARN MORE
July 22, 2016 Mystery Solved: Chemotherapy and Immunotherapy Partners in Crime to Kill Advanced Cancer Cancer cells have the ability to evade the immune system by exploiting a self-regulatory mechanism that immune cells ... LEARN MORE
July 15, 2016 Warming up the Issue of Heat Loss Obesity was classified as a disease by the American Medical Association in 2013, and has become a serious epidemic ... LEARN MORE
July 7, 2016 Cancer Cell Lines: Immortal Champions in Oncology Drug Discovery Human cancer cell lines are a powerful model system that can be propagated virtually indefinitely in culture, and manipulated to assess sensitivity to anticancer drugs or to investigate the molecular factors behind response to therapy. Oncology research using cancer cell lines has provided meaningful insights into many aspects of cancer susceptibility to ... LEARN MORE
May 19, 2016 Large-Scale Screening Using Patient Avatars Aid Clinical Trial Design As scientists are learning about the heterogeneity between patients that supposedly have the same tumor, they are ... LEARN MORE
May 10, 2016 Can We Conquer Drug Resistance in Lung Cancer? At the beginning of the last century lung cancer was a rare disease. However, as early as the end of the 1900s, it had ... LEARN MORE
March 8, 2016 Novo Nordisk Leads the Way to Cardiovascular Safety in Diabetes Treatment Diabetes is one of the largest global health emergencies of the 21st century. Every year an increasing number of people ... LEARN MORE
January 20, 2016 Avatar Trial Identifies New Treatment Route for Melanoma Patients Melanoma accounts for approximately five percent of all skin cancer cases, yet it is responsible for nearly 75 percent of skin cancer-related deaths. The BRAF gene is frequently mutated in melanoma, leading to aberrant activation of an important growth pathway. Melanoma patients who receive treatment with targeted therapies that inhibit activated BRAF ... LEARN MORE
December 16, 2015 The Bloody Business Of Tandem Duplications in Acute Myeloid Leukemia Acute myeloid leukemia (AML) is the most common form of aggressive hematologic malignancy affecting adults. AML is ... LEARN MORE
December 8, 2015 Syngeneic Models Take Center Stage In Immunotherapy Syngeneic models were developed over 50 years ago as early in vivo models for oncology drug development, consisting of ... LEARN MORE
December 1, 2015 Fatty Liver Disease And The Need for New Translational Models Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in developed countries, occurring when fat ... LEARN MORE
November 24, 2015 Epithelial To Mesenchymal Transition: A Step Back For Cancer Cells, A Step Forward For Drug Discovery Metastasis remains the main cause of cancer-related mortality, despite major scientific advances in the understanding ... LEARN MORE