December 3, 2020
The Latest Developments on PARP Inhibitors for Prostate Cancer Treatment
Review the status of PARP inhibitors (PARPi) for prostate cancer treatment, with a focus on recent developments in drug approvals and published data.
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October 26, 2020
Applications and Benefits of Engineered Syngeneic Cell Lines
Explore the use and main benefits of engineered syngeneic cell lines for investigating drug targets and biological ...
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July 10, 2020
Immunogenomics in Oncology Drug Development
Explore the emerging field of immunogenomics and how it’s being used to answer key questions related to immunotherapy ...
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April 28, 2020
PARP Inhibitors: Where Are We in 2020 and What’s Coming Next?
Review the current approval status of PARP inhibitors, and what could be coming next for this class of agent, including ...
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February 13, 2020
Targeting KRAS: Finally Drugging the Undruggable?
Targeting KRAS - As promising clinical trial data emerges for KRAS G12C inhibitors, we review the background, recent ...
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November 22, 2019
The Importance of Companion Diagnostics
Explore the importance of companion diagnostics (CDx) and the benefits of their early adoption and drug codevelopment.
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October 4, 2019
What are PDX-Derived Organoids (PDXOs)?
Learn about PDX-derived organoids, including PDXO establishment and utility in a pioneering drug discovery platform combining the benefits of in vitro PDXO and highly predictive in vivo PDX models.
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September 19, 2019
Key Discoveries in the Development of Modern HUB Organoids
Learn about the key research discoveries leading to the development of modern HUB Organoids.
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August 29, 2019
Key Applications of Organoids
Explore the key applications of organoids, which are increasingly being used as in vitro models of human development ...
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August 22, 2019
How Do HUB Organoids Differ from Other Organoid Cultures?
Explore the similarities and differences between the Hubrecht Organoid Technology (HUB) approach and other commonly ...
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August 15, 2019
How are Organoids Different from Spheroids?
Explore the similarities and differences between organoids and spheroids - the most commonly used approaches for establishing 3D cell culture systems.
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August 8, 2019
The Development of HUB Organoids
Review the development and use of HUB Organoids, from the first discovery of Lgr5 as an adult stem cell biomarker in ...
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July 18, 2019
Tumor Organoids and the HUB Protocol Method
Review organoid culture techniques and applications, with a focus on tumor organoids developed via HUB protocols.
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