April 28, 2020
PARP Inhibitors: Where Are We in 2020 and What’s Coming Next?
Review the current approval status of PARP inhibitors, and what could be coming next for this class of agent, including combination regimens
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February 13, 2020
Targeting KRAS: Finally Drugging the Undruggable?
Targeting KRAS - As promising clinical trial data emerges for KRAS G12C inhibitors, we review the background, recent ...
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November 22, 2019
The Importance of Companion Diagnostics
Explore the importance of companion diagnostics (CDx) and the benefits of their early adoption and drug codevelopment.
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October 4, 2019
What are PDX-Derived Organoids (PDXOs)?
Learn about PDX-derived organoids, including PDXO establishment and utility in a pioneering drug discovery platform ...
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September 19, 2019
Key Discoveries in the Development of Modern HUB Organoids
Learn about the key research discoveries leading to the development of modern HUB Organoids.
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August 29, 2019
Key Applications of Organoids
Explore the key applications of organoids, which are increasingly being used as in vitro models of human development ...
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August 22, 2019
How Do HUB Organoids Differ from Other Organoid Cultures?
Explore the similarities and differences between the Hubrecht Organoid Technology (HUB) approach and other commonly used methods for establishing organoid cultures.
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August 15, 2019
How are Organoids Different from Spheroids?
Explore the similarities and differences between organoids and spheroids - the most commonly used approaches for ...
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August 8, 2019
The Development of HUB Organoids
Review the development and use of HUB Organoids, from the first discovery of Lgr5 as an adult stem cell biomarker in ...
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July 18, 2019
Tumor Organoids and the HUB Protocol Method
Review organoid culture techniques and applications, with a focus on tumor organoids developed via HUB protocols.
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