March 1, 2021
Profiling of Tumor-Infiltrating Immune Cells in Syngeneic Tumor Models to Support Drug Development
Tumor-Infiltrating Immune Cells: Explore how the identification and quantification of tumor-infiltrating lymphocytes (TILs) can help evaluating the efficacy of novel immunotherapy agents.
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November 6, 2020
In Vivo Imaging of Syngeneic Models for Immuno-Oncology Studies
Explore how different imaging modalities are used to monitor in vivo immuno-oncology (I/O) studies in syngeneic tumor ...
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July 16, 2020
Next Generation Sequencing 101
A look at the range of next-generation sequencing technologies available today including whole genome, RNA, and whole ...
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April 24, 2020
Modeling Oncogenic RAS and BRAF Mutations Using Colorectal Cancer Organoids
Explore how genetically engineered patient-derived tumor organoids are helping to model colorectal cancer and specific ...
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February 11, 2020
huPBMC Humanized Mouse Models: De-Risking Graft versus Tumor (GvT) Effects Through a Co-Culture Donor Selection Assay
Explore how to use a donor selection assay to limit the chances of graft vs tumor (GvT) effects when using huPBMC ...
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October 24, 2019
Graft-versus-Host Disease: Types and How to Model Them
Review the different types of graft-versus-host disease (GvHD) and the preclinical models (including humanized mice) ...
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July 26, 2019
Targeting the CD47/SIRPɑ Axis in Cancer Immunotherapy
Explore why the CD47/SIRPα axis is an important immuno-oncology target and the methods being used to block this axis.
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March 14, 2019
LAG3: A Promising New Cancer Immunotherapy Target
As we continue our discussion of the immune revolution in cancer therapy, we look at the benefits of targeting LAG3, an ...
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February 7, 2019
CD40: Targeting Co-Stimulatory Pathways for Cancer Immunotherapy
Explore the role of CD40 in cancer immunotherapy, including its background, functions, and why combination regimens may ...
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