Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

September 4, 2019 Mouse Models of Inflammatory Bowel Disease Mouse Models of Inflammatory Bowel Disease Review the wide variety of inflammatory bowel disease mouse models available, and the unique characteristics which make different models ideally suited to specific study types. LEARN MORE
August 27, 2019 Banana Tolerance Test: A New Stress-Free OGTT Method Banana Tolerance Test: A New Stress-Free OGTT Method Learn more about the banana tolerance test, which shares ... LEARN MORE
August 13, 2019 Continuous Glucose Monitoring in NHP Models Discover continuous glucose monitoring as an enhanced technique for preclinical blood glucose measurement in NHP models ... LEARN MORE
July 9, 2019 CAR-T Cell Therapy for Pancreatic Cancer Explore how CAR-T cell therapy is showing promise as a novel treatment strategy for pancreatic cancer. LEARN MORE
June 11, 2019 Orthotopic or Subcutaneous Tumor Homograft Models? When should you use either subcutaneous or orthotopic pancreatic cancer tumor homografts, and where do they best ... LEARN MORE
April 3, 2019 New Analysis, Model ID, and Modeling Technologies at AACR 2019 In Atlanta this week we’re presenting data on our new analysis platforms and preclinical technologies. This post recaps ... LEARN MORE
April 2, 2019 Syngeneic and Tumor Homograft Immuno-Oncology Models at AACR 2019 Recap all our AACR presentations on murine models including bioluminescent orthotopic syngeneic models, syngeneic model research into immune cell lineage impact on anti-PD-1 response, and prostate cancer tumor homograft models. LEARN MORE
April 1, 2019 Humanized Model Update at AACR 2019 Review all the new data on our humanized target models for human-specific CD40 and combination regimen assessment, and ... LEARN MORE
April 1, 2019 AACR19 Analysis: PDX and PDX-Derived Organoid Models Review all the new data on patient-derived xenograft (PDX) models we’re presenting at AACR 2019 this week, including ... LEARN MORE
March 6, 2019 Using Genetic Features to ID and QC Murine Tumor Models Learn how unique genetic events can be used to generate a “genetic fingerprint” to ID and QC murine tumor models. LEARN MORE
March 1, 2019 Novel Uses for PDX Models in Preclinical Drug Development Learn how unique PDX models are used to support clinical drug development, discover predictive gene signatures, and for tumor microenvironment investigations. LEARN MORE
February 5, 2019 Beginners Guide to PBMC Humanized Tumor Models Discover PBMC-humanized tumor models for short-term immunotherapy assessment studies. LEARN MORE
January 31, 2019 How to Test Human-Specific Combination Immunotherapies In Vivo Learn how to evaluate combinations of human-specific checkpoint inhibitors in vivo, with double knock-in humanized drug ... LEARN MORE
December 24, 2018 NASH 2018 Review: Improving Awareness and Potential New Therapies A look back at NASH over the course of 2018, with a focus on raising disease awareness and an update on clinical trial ... LEARN MORE
November 15, 2018 Prostate Cancer PDX Models and Oncology Analysis Studies: ENA 2018 This week at ENA 2018, we’re presenting up to date research on our PDX models, including our newly developed prostate ... LEARN MORE