Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

September 11, 2019 HUB Organoids: Top 9 Technical Questions Review the top 9 technical questions on HUB organoid development from our recent webinar, answered by Dr Sylvia Boj, Scientific Director of Hubrecht Organoid Technology (HUB). LEARN MORE
September 4, 2019 Mouse Models of Inflammatory Bowel Disease Mouse Models of Inflammatory Bowel Disease Review the wide variety of inflammatory bowel disease mouse models ... LEARN MORE
July 9, 2019 CAR-T Cell Therapy for Pancreatic Cancer Explore how CAR-T cell therapy is showing promise as a novel treatment strategy for pancreatic cancer. LEARN MORE
June 11, 2019 Orthotopic or Subcutaneous Tumor Homograft Models? When should you use either subcutaneous or orthotopic pancreatic cancer tumor homografts, and where do they best ... LEARN MORE
April 3, 2019 New Analysis, Model ID, and Modeling Technologies at AACR 2019 In Atlanta this week we’re presenting data on our new analysis platforms and preclinical technologies. This post recaps ... LEARN MORE
April 2, 2019 Syngeneic and Tumor Homograft Immuno-Oncology Models at AACR 2019 Recap all our AACR presentations on murine models including bioluminescent orthotopic syngeneic models, syngeneic model ... LEARN MORE
April 1, 2019 Humanized Model Update at AACR 2019 Review all the new data on our humanized target models for human-specific CD40 and combination regimen assessment, and how we’re using PBMC and HSC humanized mice to model graft vs host disease. LEARN MORE
April 1, 2019 AACR19 Analysis: PDX and PDX-Derived Organoid Models Review all the new data on patient-derived xenograft (PDX) models we’re presenting at AACR 2019 this week, including ... LEARN MORE
March 6, 2019 Using Genetic Features to ID and QC Murine Tumor Models Learn how unique genetic events can be used to generate a “genetic fingerprint” to ID and QC murine tumor models. LEARN MORE
March 1, 2019 Novel Uses for PDX Models in Preclinical Drug Development Learn how unique PDX models are used to support clinical drug development, discover predictive gene signatures, and for ... LEARN MORE
February 5, 2019 Beginners Guide to PBMC Humanized Tumor Models Discover PBMC-humanized tumor models for short-term immunotherapy assessment studies. LEARN MORE
January 31, 2019 How to Test Human-Specific Combination Immunotherapies In Vivo Learn how to evaluate combinations of human-specific checkpoint inhibitors in vivo, with double knock-in humanized drug ... LEARN MORE
November 15, 2018 Prostate Cancer PDX Models and Oncology Analysis Studies: ENA 2018 This week at ENA 2018, we’re presenting up to date research on our PDX models, including our newly developed prostate ... LEARN MORE
November 15, 2018 Murine Immuno-Oncology Models: ENA 2018 At ENA 2018 we’re presenting new data on our wide range of immuno-oncology (I/O) platforms, with four posters covering ... LEARN MORE
November 14, 2018 Humanized Immuno-Oncology Model Update: ENA 2018 This week, at ENA Dublin 2018, we’re presenting new data from our novel humanized in vivo preclinical platforms. This ... LEARN MORE