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Blog

Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology and CVMD

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September 17, 2020 HUB Technology: The Only Tumor Organoid Platform Available for Oncology Drug Discovery Explore why adult stem cell (ASC)-derived HUB technology provides the only tumor organoid platform available for oncology drug discovery. LEARN MORE
August 27, 2020 Tumor Organoid Applications in Cancer Research Explore tumor organoid applications in cancer research including metastasis modeling, drug screening, understanding ... LEARN MORE
August 20, 2020 Why Choose Tumor Organoids vs Other 3D In Vitro Models for Oncology Drug Development Review the key differences between tumor organoids and other 3D in vitro tumor cell cultures, including spheroids, ... LEARN MORE
August 12, 2020 How to Select the Right In Vivo PDX Using PDX-Derived Organoids (PDXO) Select the right in vivo PDX: Explore how 3D in vitro tumor organoids are used to guide in vivo PDX model selection. LEARN MORE
May 15, 2020 Top 3 Ways to Use Tumor Organoids for Drug Screening Explore the top 3 ways to use tumor organoids for drug screening: library screening, efficacy quantification screening, ... LEARN MORE
May 7, 2020 Top 4 Applications for Tumor Organoids in Oncology Drug Development Explore the main applications for tumor organoids in preclinical cancer drug development, driven by the unique features ... LEARN MORE
February 27, 2020 The Benefits of PDX Models in Head and Neck Cancer Research Explore why patient-derived xenografts (PDX) are an important model in head and neck cancer research, particularly for studying radiation response and deriving next generation organoids. LEARN MORE
February 25, 2020 Using Organoids to Understand Colorectal Cancer Mechanisms and Development Learn how healthy tissue and tumor-derived organoids are used to uncover disease mechanisms, here shining a light on ... LEARN MORE
February 20, 2020 Identify Predictive Biomarkers Using Translational Preclinical Models Explore a variety of methods to identify predictive biomarkers using a range of translational preclinical models ... LEARN MORE
February 18, 2020 Using Liver-Targeted Mitochondrial Uncoupling to Resolve Fatty Liver Disease Explore how liver-targeted mitochondrial uncoupling is resolving fatty liver disease in preclinical models, with the ... LEARN MORE
February 6, 2020 How to Use Mouse Clinical Trials to Reinterpret Clinical Results Explore how to use mouse clinical trials and analysis by linear mixed models approaches to reinterpret clinical trial results, including failed trials and for biomarker validation. LEARN MORE
February 4, 2020 How to Quantify Drug Efficacy and Effects in Mouse Clinical Trials Learn how to correctly quantify drug efficacy and effects in mouse clinical trials using a linear mixed models ... LEARN MORE
January 31, 2020 How to Optimize Mouse Clinical Trial Study Design Learn how to optimize mouse clinical trial study design, including choosing how many PDX to use, via a linear mixed ... LEARN MORE
January 29, 2020 Mouse Clinical Trial Analysis Explore the current methods of mouse clinical trial analysis, and how these are improved by using a linear mixed models ... LEARN MORE
October 29, 2019 Advances in In Vivo Oncology Models at AACR-NCI-EORTC 2019 In Boston this week we’re presenting all the latest updates across our panels of in vivo oncology models. Catch up with ... LEARN MORE