October 28, 2019
New Organoid Platforms for Oncology and I/O Drug Discovery at AACR-NCI-EORTC 2019
2019 has been an exciting year at CrownBio with the addition of organoid platforms to our portfolio of models and services. We’re presenting our latest organoid progress updates with two posters at this year’s AACR-NCI-EORTC meeting in Boston.
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December 20, 2018
Immunotherapy 2018 Review: From the Nobel Prize to Clinical Trial Failures
2018 has been a roller coaster year for immunotherapy, from exciting Nobel Prize news to warning IDO1 clinical trial ...
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October 6, 2016
Breast Cancer No Longer Scary as we Reveal Its Smarter Disguises
October is breast cancer awareness month and CrownBio has reviewed the latest breast cancer research to bring you the ...
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September 27, 2016
All You Need to Know About Non-Alcoholic Fatty Liver Disease
Non-Alcoholic Fatty liver disease (NAFLD) is a complex condition where an excessive amount of fat accumulates in the ...
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September 13, 2016
Obesity Linked To Self-Eating Beige Fat
Humans, like all mammals, have two types of fat with completely opposite functions: white, which stores energy and when ...
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September 6, 2016
All About Leukemia for Childhood Cancer Month
September is Childhood Cancer Awareness Month, raising awareness and providing time for discussion on this deadly group ...
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August 23, 2016
Put Your Glasses On, Tumor Pharmacology Goes 3D
Attrition rates in oncology drug development are higher than in other disease areas, with almost 95% of compounds showing preclinical activity failing to reach clinical development. This indicates a disconnect between current preclinical models and tumors in patients. CrownBio, in collaboration with the University of Nottingham, has recently developed a ...
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August 2, 2016
Study Finds Perfect Therapeutic Match To Fight a Common Form of Leukemia
Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer, characterized by an excessive ...
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July 22, 2016
Mystery Solved: Chemotherapy and Immunotherapy Partners in Crime to Kill Advanced Cancer
Cancer cells have the ability to evade the immune system by exploiting a self-regulatory mechanism that immune cells ...
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July 15, 2016
Warming up the Issue of Heat Loss
Obesity was classified as a disease by the American Medical Association in 2013, and has become a serious epidemic ...
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July 7, 2016
Cancer Cell Lines: Immortal Champions in Oncology Drug Discovery
Human cancer cell lines are a powerful model system that can be propagated virtually indefinitely in culture, and manipulated to assess sensitivity to anticancer drugs or to investigate the molecular factors behind response to therapy. Oncology research using cancer cell lines has provided meaningful insights into many aspects of cancer susceptibility to ...
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May 19, 2016
Large-Scale Screening Using Patient Avatars Aid Clinical Trial Design
As scientists are learning about the heterogeneity between patients that supposedly have the same tumor, they are ...
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May 10, 2016
Can We Conquer Drug Resistance in Lung Cancer?
At the beginning of the last century lung cancer was a rare disease. However, as early as the end of the 1900s, it had ...
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March 8, 2016
Novo Nordisk Leads the Way to Cardiovascular Safety in Diabetes Treatment
Diabetes is one of the largest global health emergencies of the 21st century. Every year an increasing number of people ...
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January 20, 2016
Avatar Trial Identifies New Treatment Route for Melanoma Patients
Melanoma accounts for approximately five percent of all skin cancer cases, yet it is responsible for nearly 75 percent ...
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