August 15, 2019
How are Organoids Different from Spheroids?
Explore the similarities and differences between organoids and spheroids - the most commonly used approaches for establishing 3D cell culture systems.
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August 8, 2019
The Development of HUB Organoids
Review the development and use of HUB Organoids, from the first discovery of Lgr5 as an adult stem cell biomarker in ...
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July 26, 2019
Targeting the CD47/SIRPɑ Axis in Cancer Immunotherapy
Explore why the CD47/SIRPα axis is an important immuno-oncology target and the methods being used to block this axis.
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July 19, 2019
Recapitulating Clinical Metastatic Events in Preclinical Mouse Models
Explore the preclinical mouse models that best recapitulate the progression of the clinical metastatic process.
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July 18, 2019
Tumor Organoids and the HUB Protocol Method
Review organoid culture techniques and applications, with a focus on tumor organoids developed via HUB protocols.
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July 9, 2019
CAR-T Cell Therapy for Pancreatic Cancer
Explore how CAR-T cell therapy is showing promise as a novel treatment strategy for pancreatic cancer.
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June 11, 2019
Orthotopic or Subcutaneous Tumor Homograft Models?
When should you use either subcutaneous or orthotopic pancreatic cancer tumor homografts, and where do they best support your drug discovery workflow?
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May 30, 2019
Key Differences between hPBMC and hCD34 Humanized Mouse Models
Learn more about the different human immune cell populations in PBMC and HSC-humanized mouse models, to help select the ...
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May 7, 2019
Combination Therapies and Tumor Homograft Models
Learn more about using tumor homograft models to assess oncology combination regimens, including immunotherapies.
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April 25, 2019
Large-Scale Immunotherapy Screening: How and Why?
Learn more about the need for large-scale cancer immunotherapy screens and the different immunocompetent models ...
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April 16, 2019
5 Criteria for Choosing a Contract Research Organization
Contract research organizations (CROs) vary in capability, quality, experience, cost, and ease of collaboration. Weigh these five criteria to determine if a CRO is a good fit for your specific project.
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April 3, 2019
New Analysis, Model ID, and Modeling Technologies at AACR 2019
In Atlanta this week we’re presenting data on our new analysis platforms and preclinical technologies. This post recaps ...
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April 2, 2019
Syngeneic and Tumor Homograft Immuno-Oncology Models at AACR 2019
Recap all our AACR presentations on murine models including bioluminescent orthotopic syngeneic models, syngeneic model ...
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April 1, 2019
Humanized Model Update at AACR 2019
Review all the new data on our humanized target models for human-specific CD40 and combination regimen assessment, and ...
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April 1, 2019
AACR19 Analysis: PDX and PDX-Derived Organoid Models
Review all the new data on patient-derived xenograft (PDX) models we’re presenting at AACR 2019 this week, including ...
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