Welcome to CrownBio’s Blog where we share our thoughts
on the latest trends and hot stories in Oncology

June 11, 2020 DNA Damage Response (DDR) Explore how various cellular DNA damage response (DDR) and DNA repair pathways are targeted to develop novel anticancer therapeutic strategies. LEARN MORE
June 8, 2020 Using Tumor Organoids to Identify Cancer Biomarkers Review why and how to use 3D in vitro tumor organoids to identify cancer biomarkers. LEARN MORE
May 15, 2020 Top 3 Ways to Use Tumor Organoids for Drug Screening Explore the top 3 ways to use tumor organoids for drug screening: library screening, efficacy quantification screening, ... LEARN MORE
May 7, 2020 Top 4 Applications for Tumor Organoids in Oncology Drug Development Explore the main applications for tumor organoids in preclinical cancer drug development, driven by the unique features ... LEARN MORE
May 5, 2020 HUB Organoids as Human Cancer Models Explore the phenotypic and genetic concordance between HUB patient-derived tumor organoids and the primary human ... LEARN MORE
April 30, 2020 How to Use Tumor Organoids for Immuno-Oncology Applications Explore how to use tumor organoids for immuno-oncology applications, including immunotherapy assessment through ... LEARN MORE
April 28, 2020 PARP Inhibitors: Where Are We in 2020 and What’s Coming Next? Review the current approval status of PARP inhibitors, and what could be coming next for this class of agent, including combination regimens LEARN MORE
April 24, 2020 Modeling Oncogenic RAS and BRAF Mutations Using Colorectal Cancer Organoids Explore how genetically engineered patient-derived tumor organoids are helping to model colorectal cancer and specific ... LEARN MORE
April 22, 2020 The Role of Proteomics in Oncology Biomarker Discovery Explore the evolving role of proteomics in oncology biomarker discovery, specifically identifying and analyzing ... LEARN MORE
April 1, 2020 The Role of Patient-Derived Tumor Organoids in Precision Medicine Explore how patient-derived tumor organoids are used in the clinic to develop novel precision medicine approaches for ... LEARN MORE
March 16, 2020 Tumor Organoid Q&A: PDXO Models and Immuno-Oncology Applications Review the key questions and answers on PDX-derived organoids (PDXO) and tumor organoid immuno-oncology applications from our recent webinar on 3D in vitro drug discovery. LEARN MORE
March 12, 2020 Top 10 Questions: HUB Organoid Technology and Models Dr Rajendra Kumari answers the key questions around HUB Organoid technology and tumor organoid models from our recent ... LEARN MORE
March 6, 2020 How to Develop Predictive Cancer Biomarkers How to develop predictive cancer biomarkers: Explore the different types and classes of cancer biomarker, and the key ... LEARN MORE
February 27, 2020 The Benefits of PDX Models in Head and Neck Cancer Research Explore why patient-derived xenografts (PDX) are an important model in head and neck cancer research, particularly for ... LEARN MORE
February 25, 2020 Using Organoids to Understand Colorectal Cancer Mechanisms and Development Learn how healthy tissue and tumor-derived organoids are used to uncover disease mechanisms, here shining a light on ... LEARN MORE