October 4, 2019
What are PDX-Derived Organoids (PDXOs)?
Learn about PDX-derived organoids, including PDXO establishment and utility in a pioneering drug discovery platform combining the benefits of in vitro PDXO and highly predictive in vivo PDX models.
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September 19, 2019
Key Discoveries in the Development of Modern HUB Organoids
Learn about the key research discoveries leading to the development of modern HUB Organoids.
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September 17, 2019
Targeting Tumor-Associated Antigens and Tumor-Specific Antigens
Learn more about targeting human tumor-associated antigens (TAAs) or tumor-specific antigens (TSAs) in immunotherapy ...
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September 13, 2019
HUB Tumor Organoids: Top 15 Questions
Review the key questions on HUB tumor organoids from our recent webinar, answered by Dr Sylvia Boj, Hubrecht Organoid ...
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September 11, 2019
HUB Organoids: Top 9 Technical Questions
Review the top 9 technical questions on HUB organoid development from our recent webinar, answered by Dr Sylvia Boj, ...
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September 10, 2019
How to Assess Immunotherapy Toxicity with NHP Models
How to Assess Immunotherapy Toxicity with NHP Models Explore non-GLP exploratory toxicology NHP studies as a rapid and ...
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August 29, 2019
Key Applications of Organoids
Explore the key applications of organoids, which are increasingly being used as in vitro models of human development and diseases, such as cancer.
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August 22, 2019
How Do HUB Organoids Differ from Other Organoid Cultures?
Explore the similarities and differences between the Hubrecht Organoid Technology (HUB) approach and other commonly ...
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August 20, 2019
Circulating Tumor Cells in Preclinical Mouse Models of Metastasis
Explore the utility of preclinical mouse models of metastasis to study circulating tumor cells (CTCs) and the ...
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August 15, 2019
How are Organoids Different from Spheroids?
Explore the similarities and differences between organoids and spheroids - the most commonly used approaches for ...
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August 8, 2019
The Development of HUB Organoids
Review the development and use of HUB Organoids, from the first discovery of Lgr5 as an adult stem cell biomarker in the Clevers lab, to the model features and data which have led to their widespread use today.
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July 26, 2019
Targeting the CD47/SIRPɑ Axis in Cancer Immunotherapy
Explore why the CD47/SIRPα axis is an important immuno-oncology target and the methods being used to block this axis.
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July 19, 2019
Recapitulating Clinical Metastatic Events in Preclinical Mouse Models
Explore the preclinical mouse models that best recapitulate the progression of the clinical metastatic process.
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July 18, 2019
Tumor Organoids and the HUB Protocol Method
Review organoid culture techniques and applications, with a focus on tumor organoids developed via HUB protocols.
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July 9, 2019
CAR-T Cell Therapy for Pancreatic Cancer
Explore how CAR-T cell therapy is showing promise as a novel treatment strategy for pancreatic cancer.
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